Host Adaptation and the Alteration of Viral Properties of the First Influenza A/H1N1pdm09 Virus Isolated in Japan.

A/Narita/1/2009 (A/N) was the first H1N1 virus from the 2009 pandemic (H1pdm) to be isolated in Japan. To better understand and predict the possible development of this virus strain, the effect of passaging A/N was investigated in Madin-Darby canine kidney cells, chicken eggs and mice. A/N that had...

Full description

Bibliographic Details
Main Authors: Akira Ainai, Hideki Hasegawa, Masatsugu Obuchi, Takato Odagiri, Makoto Ujike, Masayuki Shirakura, Eri Nobusawa, Masato Tashiro, Hideki Asanuma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4469301?pdf=render