Assessment of peripheral airway function following chronic allergen challenge in a sheep model of asthma.

BACKGROUND: There is increasing evidence that the small airways contribute significantly to the pathophysiology of asthma. However, due to the difficulty in accessing distal lung regions in clinical settings, functional changes in the peripheral airways are often overlooked in studies of asthmatic p...

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Bibliographic Details
Main Authors: Joanne Van der Velden, Donna Barker, Garry Barcham, Emmanuel Koumoundouros, Kenneth Snibson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3236205?pdf=render