An investigation of a role for U2 snRNP spliceosomal components in regulating transcription.

There is mounting evidence to suggest that the synthesis of pre-mRNA transcripts and their subsequent splicing are coordinated events. Previous studies have implicated the mammalian spliceosomal U2 snRNP as having a novel role in stimulating transcriptional elongation in vitro through interactions w...

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Bibliographic Details
Main Authors: Susannah L McKay, Tracy L Johnson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3025917?pdf=render