Collagen/heparan sulfate porous scaffolds loaded with neural stem cells improve neurological function in a rat model of traumatic brain injury

Collagen/heparan sulfate porous scaffolds loaded with neural stem cells improve neurological function in a rat model of traumatic brain injury

One reason for the poor therapeutic effects of stem cell transplantation in traumatic brain injury is that exogenous neural stem cells cannot effectively migrate to the local injury site, resulting in poor adhesion and proliferation of neural stem cells at the injured area. To enhance the targeted d...

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Bibliographic Details
Main Authors: Jian Zhang, Ren-Jie Wang, Miao Chen, Xiao-Yin Liu, Ke Ma, Hui-You Xu, Wu-Sheng Deng, Yi-Chao Ye, Wei-Xin Li, Xu-Yi Chen, Hong-Tao Sun
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
collagen; heparan sulfate; injury; neural stem cells; regeneration; repair; scaffold; traumatic brain injury; morris water maze; motor evoked potential; synapses; myelin sheaths
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=6;spage=1068;epage=1077;aulast=

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=6;spage=1068;epage=1077;aulast=

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