Spectrum and characterisation of <it>BRCA1 </it>and <it>BRCA2 </it>deleterious mutations in high-risk Czech patients with breast and/or ovarian cancer

<p>Abstract</p> <p>Background</p> <p>The incidence of breast cancer has doubled over the past 20 years in the Czech Republic. Hereditary factors may be a cause of young onset, bilateral breast or ovarian cancer, and familial accumulation of the disease. <it>BRCA1...

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Bibliographic Details
Main Authors: Kosinova Veronika, Pavlu Hana, Coene Ilse, Navratilova Marie, Vasickova Petra, Lukesova Mirka, Foretova Lenka, Machackova Eva, Kuklova Jitka, Claes Kathleen
Format: Article
Language:English
Published: BMC 2008-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/140