Functional omics analyses reveal only minor effects of microRNAs on human somatic stem cell differentiation

Abstract The contribution of microRNA-mediated posttranscriptional regulation on the final proteome in differentiating cells remains elusive. Here, we evaluated the impact of microRNAs (miRNAs) on the proteome of human umbilical cord blood-derived unrestricted somatic stem cells (USSC) during retino...

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Bibliographic Details
Main Authors: Jessica Schira-Heinen, Agathe Czapla, Marion Hendricks, Andreas Kloetgen, Wasco Wruck, James Adjaye, Gesine Kögler, Hans Werner Müller, Kai Stühler, Hans-Ingo Trompeter
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-60065-8