Comparative Phenotype and Immunogenicity of Freshly Isolated and Immortalized Rat Hepatocytes

Immortalized hepatocytes are an attractive cell source for hepatocyte transplantation and gene transfer. We compared the phenotype and immunogenicity of freshly isolated (FIH) and immortalized (IMH) rat hepatocytes. Effect of culture and proinflammatory cytokines (TNF-α, IFN-γ) was studied on phenot...

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Bibliographic Details
Main Authors: Vincent Kaulek, Philippe Saas, Eliane Alexandre, Helen Grant, Lysiane Richert, Daniel Jaeck, Pierre Tiberghien, Philippe Wolf, Agnès Azimzadeh
Format: Article
Language:English
Published: SAGE Publishing 2001-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000001783986242