Retrobulbar administration of purified anti-nerve growth factor in developing rats induces structural and biochemical changes in the retina and cornea

AIM: To develop an experimental model of endogenous nerve growth factor (NGF) deprivation by retrobulbar administration of purified neutralizing anti-NGF antibodies in young Sprague-Dawley rats and provide further information on NGF expression in the retina and cornea. METHODS: Sixty old pathogen-fr...

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Bibliographic Details
Main Authors: Luigi Aloe, Maria Luisa Rocco, Bijorn Omar Balzamino, Graziana Esposito, Alessandra Micera
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-02-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://ies.ijo.cn/en_publish/2021/2/20210205.pdf