Paracoccidioides brasiliensis Releases a DNase-Like Protein That Degrades NETs and Allows for Fungal Escape

Paracoccidioides brasiliensis Releases a DNase-Like Protein That Degrades NETs and Allows for Fungal Escape

Paracoccidioidomycosis is a systemic fungal disease, considered endemic in Latin America. Its etiological agents, fungi of the Paracoccidioides complex, have restricted geographic habitat, conidia as infecting form, and thermo-dimorphic characteristics. Polymorphonuclear neutrophils (PMNs) are respo...

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Bibliographic Details
Main Authors: Yohan Ricci Zonta, Ana Laura Ortega Dezen, Amanda Manoel Della Coletta, Kaio Shu Tsyr Yu, Larissa Carvalho, Leandro Alves dos Santos, Igor de Carvalho Deprá, Rachel M. Kratofil, Michelle Elizabeth Willson, Lori Zbytnuik, Paul Kubes, Valdecir Farias Ximenes, Luciane Alarcão Dias-Melicio
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
paracoccidioidomycosis
neutrophils
neutrophil extracellular traps (NETs)
DNase
escape mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.592022/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2020.592022/full

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