Combinatorial delivery of antigen and TLR agonists via PLGA nanoparticles modulates Leishmania major-infected-macrophages activation

Combinatorial delivery of antigen and TLR agonists via PLGA nanoparticles modulates Leishmania major-infected-macrophages activation

Appropriate activation of macrophages is critical for the elimination of Leishmania parasites, which resides in this cell. Some species of Leishmania (L.) fails to stimulate macrophages and establish a chronic infection. To overcome this suppression and induce an innate immune response, the effect o...

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Bibliographic Details
Main Authors: Asal Katebi, Reyhaneh Varshochian, Farhad Riazi-rad, Mazdak Ganjalikhani-Hakemi, Soheila Ajdary
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
PLGA
Nanoparticles
Leishmania major
Pasm3csk4
R848
Pro-inflammatory cytokines
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221000615

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http://www.sciencedirect.com/science/article/pii/S0753332221000615

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