The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning.

Anaplastic Lymphoma Kinase (Alk) is a Receptor Tyrosine Kinase (RTK) activated in several cancers, but with largely unknown physiological functions. We report two unexpected roles for the Drosophila ortholog dAlk, in body size determination and associative learning. Remarkably, reducing neuronal dAl...

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Bibliographic Details
Main Authors: Jean Y Gouzi, Anastasios Moressis, James A Walker, Anthi A Apostolopoulou, Ruth H Palmer, André Bernards, Efthimios M C Skoulakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3174217?pdf=render