Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse.

BACKGROUND: Fumaric acid esters (FAE) are a group of compounds which are currently under investigation as an oral treatment for relapsing-remitting multiple sclerosis. One of the suggested modes of action is the potential of FAE to exert a neuroprotective effect. METHODOLOGY/PRINCIPAL FINDINGS: We h...

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Bibliographic Details
Main Authors: Darius Moharregh-Khiabani, Alexander Blank, Thomas Skripuletz, Elvira Miller, Alexandra Kotsiari, Viktoria Gudi, Martin Stangel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2909255?pdf=render