Fibrotic Changes to Schlemm’s Canal Endothelial Cells in Glaucoma

Fibrotic Changes to Schlemm’s Canal Endothelial Cells in Glaucoma

Previous studies have shown that glaucomatous Schlemm’s canal endothelial cells (gSCECs) are stiffer and associated with reduced porosity and increased extracellular matrix (ECM) material compared to SCECs from healthy individuals. We hypothesised that Schlemm’s canal (SC) cell stiffening was a func...

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Bibliographic Details
Main Authors: Ruth A. Kelly, Kristin M. Perkumas, Matthew Campbell, G. Jane Farrar, W. Daniel Stamer, Pete Humphries, Jeffrey O’Callaghan, Colm J. O’Brien
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
glaucoma
fibrosis
Schlemm’s canal
endothelial cells
endothelial–mesenchymal transition
proliferation
Online Access:https://www.mdpi.com/1422-0067/22/17/9446

Internet

https://www.mdpi.com/1422-0067/22/17/9446

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