P-TEFb Regulates Transcriptional Activation in Non-coding RNA Genes

P-TEFb Regulates Transcriptional Activation in Non-coding RNA Genes

Many non-coding RNAs (ncRNAs) serve as regulatory molecules in various physiological pathways, including gene expression in mammalian cells. Distinct from protein-coding RNA expression, ncRNA expression is regulated solely by transcription and RNA processing/stability. It is thus important to unders...

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Bibliographic Details
Main Authors: Heeyoun Bunch, Hyeseung Choe, Jongbum Kim, Doo Sin Jo, Soyeon Jeon, Sanghwa Lee, Dong-Hyung Cho, Keunsoo Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
non-coding RNA
RNA polymerase II promoter-proximal pausing
P-TEFb
gene expression regulation
transcriptional elongation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00342/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00342/full

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