HIF-1 signaling: A key orchestrator of cancer radioresistance
Hypoxia is a big roadblock for cancer radiotherapy, in which the hypoxia-inducible factor (HIF-1) creates a microenvironment and cancer cells’ intrinsic signaling networks conferring radioresistance to cancers. HIF-1 is a heterodimeric transcription factor HIF-1α/HIF-1β, that regulates the transcrip...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2020-03-01
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Series: | Radiation Medicine and Protection |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S266655572030006X |