Capturing change in clonal composition amongst single mouse germinal centers

Understanding cellular processes occurring in vivo on time scales of days to weeks requires repeatedly interrogating the same tissue without perturbing homeostasis. We describe a novel setup for longitudinal intravital imaging of murine peripheral lymph nodes (LNs). The formation and evolution of si...

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Bibliographic Details
Main Authors: Daniel J Firl, Soren E Degn, Timothy Padera, Michael C Carroll
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/33051