Anti-rhesus D prophylaxis in pregnant women is based on sialylated IgG antibodies [v1; ref status: indexed, http://f1000r.es/1fg]

Red blood cells (RBCs) from a rhesus D (RhD)-positive fetus that reach the bloodstream of an RhD-negative pregnant woman during birth can induce a pathogenic antibody (Ab) response against the RhD-positive RBCs, leading to fetal hemolytic disease in subsequent pregnancies. To prevent a pathogenic im...

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Bibliographic Details
Main Authors: André Winkler, Markus Berger, Marc Ehlers
Format: Article
Language:English
Published: F1000 Research Ltd 2013-08-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/2-169/v1