Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes

Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes

Abstract Background Angiostrongylus cantonensis is an important food-borne zoonotic parasite. Humans are non-permissive hosts, and this parasite develops into fifth-stage larvae (L5) in the brain and subarachnoid cavity and then induces eosinophilic meningitis and eosinophilic meningoencephalitis. E...

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Bibliographic Details
Main Authors: Kuang-Yao Chen, Yi-Ju Chen, Chien-Ju Cheng, Kai-Yuan Jhan, Lian-Chen Wang
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Parasites & Vectors
Subjects:
Angiostrongylus cantonensis
Fifth-stage larvae
Excretory/secretory products
Astrocytes
Endoplasmic reticulum stress
Sonic hedgehog pathway
Online Access:http://link.springer.com/article/10.1186/s13071-020-04189-w

Internet

http://link.springer.com/article/10.1186/s13071-020-04189-w

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