Poly-Gamma-Glutamic Acid (γ-PGA)-Based Encapsulation of Adenovirus to Evade Neutralizing Antibodies

Poly-Gamma-Glutamic Acid (γ-PGA)-Based Encapsulation of Adenovirus to Evade Neutralizing Antibodies

In recent years, there has been an increasing interest in oncolytic adenoviral vectors as an alternative anticancer therapy. The induction of an immune response can be considered as a major limitation of this kind of application. Significant research efforts have been focused on the development of b...

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Bibliographic Details
Main Authors: Ibrahim R. Khalil, Martin P. Khechara, Sathishkumar Kurusamy, Angel L. Armesilla, Abhishek Gupta, Barbara Mendrek, Tamara Khalaf, Mariastella Scandola, Maria Letizia Focarete, Marek Kowalczuk, Iza Radecka
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
biodegradable polymer
γ-PGA
chitosan
adenovirus
immunogenicity
Online Access:http://www.mdpi.com/1420-3049/23/10/2565

Internet

http://www.mdpi.com/1420-3049/23/10/2565

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