Thioredoxin interacting protein regulates age-associated neuroinflammation

Thioredoxin interacting protein regulates age-associated neuroinflammation

Immune system hypersensitivity is believed to contribute to mental frailty in the elderly. Solid evidence indicates NOD-like receptor pyrin domain containing-3 (NLRP3)-inflammasome activation intimately connects aging-associated chronic inflammation (inflammaging) to senile cognitive decline. Thiore...

Full description

Bibliographic Details
Main Authors: Saifudeen Ismael, Sanaz Nasoohi, Lexiao Li, Khurram S. Aslam, Mohammad Moshahid Khan, Azza B. El-Remessy, Michael P. McDonald, Francesca-Fang Liao, Tauheed Ishrat
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Neurobiology of Disease
Subjects:
Brain aging
TXNIP
NLRP3-inflmmasome
Oxidative stress
Functional decline
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121001480

Internet

http://www.sciencedirect.com/science/article/pii/S0969996121001480

Similar Items