40 Years of CSF Toxicity Studies in ALS: What Have We Learnt About ALS Pathophysiology?

40 Years of CSF Toxicity Studies in ALS: What Have We Learnt About ALS Pathophysiology?

Based on early evidence of in vitro neurotoxicity following exposure to serum derived from patients with amyotrophic lateral sclerosis (ALS), several studies have attempted to explore whether cerebrospinal fluid (CSF) obtained from people with ALS could possess similar properties. Although initial f...

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Bibliographic Details
Main Authors: Koy Chong Ng Kee Kwong, Pratap K. Harbham, Bhuvaneish T. Selvaraj, Jenna M. Gregory, Suvankar Pal, Giles E. Hardingham, Siddharthan Chandran, Arpan R. Mehta
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
amyotrophic lateral sclerosis
cerebrospinal fluid
motor neuron disease
neurodegeneration
pathophysiology
toxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.647895/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2021.647895/full

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