Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide

Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide

We have recently shown that a class A amphipathic peptide 5F with increased amphipathicity protected mice from diet-induced atherosclerosis (Garber et al. J. Lipid Res. 2001. 42: 545–552). We have now examined the effects of increasing the hydrophobicity of a series of homologous class A amphipathic...

Full description

Bibliographic Details
Main Authors: Geeta Datta, Manjula Chaddha, Susan Hama, Mohamad Navab, Alan M. Fogelman, David W. Garber, Vinod K. Mishra, Richard M. Epand, Raquel F. Epand, Sissel Lund-Katz, Michael C. Phillips, Jere P. Segrest, G.M. Anantharamaiah
Format: Article
Language:English
Published: Elsevier 2001-07-01
Series:Journal of Lipid Research
Subjects:
amphipathic α-helix
apoA-I analogs
hydrophobicity
LCAT
synthetic peptides
monocyte chemotactic activity
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520315996

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520315996

Similar Items