Dynamically linking influenza virus infection kinetics, lung injury, inflammation, and disease severity

Dynamically linking influenza virus infection kinetics, lung injury, inflammation, and disease severity

Influenza viruses cause a significant amount of morbidity and mortality. Understanding host immune control efficacy and how different factors influence lung injury and disease severity are critical. We established and validated dynamical connections between viral loads, infected cells, CD8+ T cells,...

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Bibliographic Details
Main Authors: Margaret A Myers, Amanda P Smith, Lindey C Lane, David J Moquin, Rosemary Aogo, Stacie Woolard, Paul Thomas, Peter Vogel, Amber M Smith
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
influenza virus
mathematical model
lung injury
lung inflammation
disease severity
CD8 T cells
Online Access:https://elifesciences.org/articles/68864

Internet

https://elifesciences.org/articles/68864

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