Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells

Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells

Abstract Background Human placenta-derived mesenchymal stem cells (PD-MSCs) are powerful sources for cell therapy in regenerative medicine. However, a limited lifespan by senescence through mechanisms that are well unknown is the greatest obstacle. In the present study, we first demonstrated the cha...

Full description

Bibliographic Details
Main Authors: Jin Seok, Hyun Sook Jung, Sohae Park, Jung Ok Lee, Chong Jai Kim, Gi Jin Kim
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Placenta-derived mesenchymal stem cell
Senescence
Mitochondria
Fatty acid
CPT1A
Online Access:https://doi.org/10.1186/s13287-019-1471-y

Internet

https://doi.org/10.1186/s13287-019-1471-y

Similar Items