Preferential and selective degradation and removal of amelogenin adsorbed on hydroxyapatites by MMP20 and KLK4 in vitro

Preferential and selective degradation and removal of amelogenin adsorbed on hydroxyapatites by MMP20 and KLK4 in vitro

The hardest tooth enamel tissue develops from a soft layer of protein-rich matrix, predominated by amelogenin that is secreted by epithelial ameloblasts in the secretory stage of tooth enamel development. During enamel formation, a well-controlled progressive removal of matrix proteins by resident p...

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Bibliographic Details
Main Authors: Li eZhu, HaiChuan eLiu, H. Ewa eWitkowska, YuLei eHuang, Kataro eTanimoto, Wu eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Physiology
Subjects:
Amelogenin
Hydroxyapatites
Mass Spectrometry
Proteolysis
Biomineralization
protein interactions
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00268/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00268/full

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