Reduction of systematic bias in transcriptome data from human peripheral blood mononuclear cells for transportation and biobanking.

Transportation of samples is essential for large-scale biobank projects. However, RNA degradation during pre-analytical operations prior to transportation can cause systematic bias in transcriptome data, which may prevent subsequent biomarker identification. Therefore, to collect high-quality bioban...

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Bibliographic Details
Main Authors: Hideki Ohmomo, Tsuyoshi Hachiya, Yu Shiwa, Ryohei Furukawa, Kanako Ono, Shigeki Ito, Yoji Ishida, Mamoru Satoh, Jiro Hitomi, Kenji Sobue, Atsushi Shimizu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4125218?pdf=render