A Novel Inflammatory Dendritic Cell That Is Abundant and Contiguous to T Cells in the Kidneys of Patients With Lupus Nephritis

A Novel Inflammatory Dendritic Cell That Is Abundant and Contiguous to T Cells in the Kidneys of Patients With Lupus Nephritis

The mechanisms that promote local inflammatory injury during lupus nephritis (LN) flare are largely unknown. Understanding the key immune cells that drive intrarenal inflammation will advance our knowledge of disease pathogenesis and inform the development of new therapeutics for LN management. In t...

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Bibliographic Details
Main Authors: Samir V. Parikh, Ana Malvar, John Shapiro, James M. Turman, Huijuan Song, Valeria Alberton, Bruno Lococo, Juan M. Mejia-Vilet, Sethu Madhavan, Jianying Zhang, Lianbo Yu, Anjali A. Satoskar, Dan Birmingham, Wael N. Jarjour, Brad H. Rovin, Latha P. Ganesan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
inflammatory dendritic cells
lupus nephritis
kidney
autoimmunity
adaptive immune response
T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.621039/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.621039/full

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