Zinc Finger CCCH-Type Antiviral Protein 1 Restricts the Viral Replication by Positively Regulating Type I Interferon Response

Zinc Finger CCCH-Type Antiviral Protein 1 Restricts the Viral Replication by Positively Regulating Type I Interferon Response

Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) is a host antiviral factor that can repress translation and promote degradation of specific viral mRNAs. In this study, we found that expression of ZC3HAV1 was significantly induced by infection with influenza A virus (IAV) and Sendai virus (Sev)....

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Bibliographic Details
Main Authors: Baoge Zhang, Mohsan Ullah Goraya, Na Chen, Lifeng Xu, Yan Hong, Meiyi Zhu, Ji-Long Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Microbiology
Subjects:
ZC3HAV1
interferon
innate immunity
influenza virus
host factor
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01912/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01912/full

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