Quantification of Beat-To-Beat Variability of Action Potential Durations in Langendorff-Perfused Mouse Hearts

Background: Beat-to-beat variability in action potential duration (APD) is an intrinsic property of cardiac tissue and is altered in pro-arrhythmic states. However, it has never been examined in mice.Methods: Left atrial or ventricular monophasic action potentials (MAPs) were recorded from Langendor...

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Bibliographic Details
Main Authors: Gary Tse, Yimei Du, Guoliang Hao, Ka Hou Christien Li, Fiona Yin Wah Chan, Tong Liu, Guangping Li, George Bazoukis, Konstantinos P. Letsas, William K. K. Wu, Shuk Han Cheng, Wing Tak Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01578/full