Leader cell PLCγ1 activation during keratinocyte collective migration is induced by EGFR localization and clustering

Leader cell PLCγ1 activation during keratinocyte collective migration is induced by EGFR localization and clustering

Abstract Re‐epithelialization is a critical step in wound healing and results from the collective migration of keratinocytes. Previous work demonstrated that immobilized, but not soluble, epidermal growth factor (EGF) resulted in leader cell‐specific activation of phospholipase C gamma 1 (PLCγ1) in...

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Bibliographic Details
Main Authors: Chloe S. Kim, Xinhai Yang, Sarah Jacobsen, Kristyn S. Masters, Pamela K. Kreeger
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Bioengineering & Translational Medicine
Subjects:
immobilized growth factor
receptor clustering
re‐epithelialization
wound healing
Online Access:https://doi.org/10.1002/btm2.10138

Internet

https://doi.org/10.1002/btm2.10138

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