Evolutionarily conserved linkage between enzyme fold, flexibility, and catalysis.
Proteins are intrinsically flexible molecules. The role of internal motions in a protein's designated function is widely debated. The role of protein structure in enzyme catalysis is well established, and conservation of structural features provides vital clues to their role in function. Recent...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-11-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC3210774?pdf=render |