ELQ-331 as a prototype for extremely durable chemoprotection against malaria

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

Abstract Background The potential benefits of long-acting injectable chemoprotection (LAI-C) against malaria have been recently recognized, prompting a call for suitable candidate drugs to help meet this need. On the basis of its known pharmacodynamic and pharmacokinetic profiles after oral dosing,...

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Bibliographic Details
Main Authors: Martin J. Smilkstein, Sovitj Pou, Alina Krollenbrock, Lisa A. Bleyle, Rozalia A. Dodean, Lisa Frueh, David J. Hinrichs, Yuexin Li, Thomas Martinson, Myrna Y. Munar, Rolf W. Winter, Igor Bruzual, Samantha Whiteside, Aaron Nilsen, Dennis R. Koop, Jane X. Kelly, Stefan H. I. Kappe, Brandon K. Wilder, Michael K. Riscoe
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium
Chemoprotection
Chemoprevention
Prophylaxis
Intra-muscular
Online Access:http://link.springer.com/article/10.1186/s12936-019-2921-9

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http://link.springer.com/article/10.1186/s12936-019-2921-9

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