A new genome scan for primary nonsyndromic vesicoureteric reflux emphasizes high genetic heterogeneity and shows linkage and association with various genes already implicated in urinary tract development

A new genome scan for primary nonsyndromic vesicoureteric reflux emphasizes high genetic heterogeneity and shows linkage and association with various genes already implicated in urinary tract development

Abstract Primary vesicoureteric reflux (VUR), the retrograde flow of urine from the bladder toward the kidneys, results from a developmental anomaly of the vesicoureteric valve mechanism, and is often associated with other urinary tract anomalies. It is the most common urological problem in children...

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Bibliographic Details
Main Authors: J. M. Darlow, M. G. Dobson, R. Darlay, C. M. Molony, M. Hunziker, A. J. Green, H. J. Cordell, P. Puri, D. E. Barton
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
CAKUT
genetic association
genetic linkage
ureteric bud
vesicoureteric reflux
Online Access:https://doi.org/10.1002/mgg3.22

Internet

https://doi.org/10.1002/mgg3.22

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