Identification of PNG kinase substrates uncovers interactions with the translational repressor TRAL in the oocyte-to-embryo transition

Identification of PNG kinase substrates uncovers interactions with the translational repressor TRAL in the oocyte-to-embryo transition

The Drosophila Pan Gu (PNG) kinase complex regulates hundreds of maternal mRNAs that become translationally repressed or activated as the oocyte transitions to an embryo. In a previous paper (Hara et al., 2017), we demonstrated PNG activity is under tight developmental control and restricted to this...

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Bibliographic Details
Main Authors: Masatoshi Hara, Sebastian Lourido, Boryana Petrova, Hua Jane Lou, Jessica R Von Stetina, Helena Kashevsky, Benjamin E Turk, Terry L Orr-Weaver
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-02-01
Series:eLife
Subjects:
Drosophila
maternal mRNA
cytoplasmic RNPs
Pumilio
ME31B
BICC
Online Access:https://elifesciences.org/articles/33150

Internet

https://elifesciences.org/articles/33150

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