Mapping HLA-A2, -A3 and -B7 supertype-restricted T-cell epitopes in the ebolavirus proteome

Mapping HLA-A2, -A3 and -B7 supertype-restricted T-cell epitopes in the ebolavirus proteome

Abstract Background Ebolavirus (EBOV) is responsible for one of the most fatal diseases encountered by mankind. Cellular T-cell responses have been implicated to be important in providing protection against the virus. Antigenic variation can result in viral escape from immune recognition. Mapping ta...

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Bibliographic Details
Main Authors: Wan Ching Lim, Asif M. Khan
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Genomics
Subjects:
Ebolavirus
T-cell epitope
HLA supertype
Antigenic diversity
Online Access:http://link.springer.com/article/10.1186/s12864-017-4328-8

Internet

http://link.springer.com/article/10.1186/s12864-017-4328-8

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