Loss of 4q21.23-22.1 is a prognostic marker for disease free and overall survival in non-small cell lung cancer.

This study was performed to assess the prognostic relevance of genomic aberrations at chromosome 4q in NSCLC patients. We have previously identified copy number changes at 4q12-q32 to be significantly associated with the early hematogenous dissemination of non-small cell lung cancer (NSCLC), and now...

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Bibliographic Details
Main Authors: Faik G Uzunoglu, Ebba Dethlefsen, Annkathrin Hanssen, Michaela Wrage, Lena Deutsch, Katharina Harms-Effenberger, Yogesh K Vashist, Matthias Reeh, Guido Sauter, Ronald Simon, Maximillian Bockhorn, Klaus Pantel, Jakob R Izbicki, Harriet Wikman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4263470?pdf=render