Development of a Bispecific Antibody Targeting CD30 and CD137 on Hodgkin and Reed-Sternberg Cells

Development of a Bispecific Antibody Targeting CD30 and CD137 on Hodgkin and Reed-Sternberg Cells

Hodgkin Lymphoma (HL) is a malignancy that frequently affects young adults. Although, there are effective treatments not every patient responds, necessitating the development of novel therapeutic approaches, especially for relapsed and refractory cases. The two TNF receptor family members CD30 and C...

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Bibliographic Details
Main Authors: Sakthi Rajendran, Yating Li, Evelyn Ngoh, Hiu Yi Wong, Man Si Cheng, Cheng-I Wang, Herbert Schwarz
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Oncology
Subjects:
Hodgkin lymphoma
CD30
CD137
bispecific antibodies
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00945/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00945/full

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