Designing Metabolic Division of Labor in Microbial Communities

Designing Metabolic Division of Labor in Microbial Communities

Understanding how microbes assemble into communities is a fundamental open issue in biology, relevant to human health, metabolic engineering, and environmental sustainability. A possible mechanism for interactions of microbes is through cross-feeding, i.e., the exchange of small molecules. These met...

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Bibliographic Details
Main Authors: Meghan Thommes, Taiyao Wang, Qi Zhao, Ioannis C. Paschalidis, Daniel Segrè
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mSystems
Subjects:
division of labor
flux balance analysis
genome-scale stoichiometric models
metabolic networks
microbiome
mixed-integer linear programming
resource allocation
synthetic ecology
microbial communities
Online Access:https://doi.org/10.1128/mSystems.00263-18

Internet

https://doi.org/10.1128/mSystems.00263-18

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