Glutathione S-Transferase M3 Is Associated with Glycolysis in Intrinsic Temozolomide-Resistant Glioblastoma Multiforme Cells

Glutathione S-Transferase M3 Is Associated with Glycolysis in Intrinsic Temozolomide-Resistant Glioblastoma Multiforme Cells

Glioblastoma multiforme (GBM) is a malignant primary brain tumor. The 5-year relative survival rate of patients with GBM remains <30% on average despite aggressive treatments, and secondary therapy fails in 90% of patients. In chemotherapeutic failure, detoxification proteins are crucial to the a...

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Bibliographic Details
Main Authors: Shu-Yu Cheng, Nan-Fu Chen, Zhi-Hong Wen, Zhi-Kang Yao, Kuan-Hao Tsui, Hsiao-Mei Kuo, Wu-Fu Chen
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
glutathione S-transferase M3
glycolysis
chemotherapeutic resistance
TMZ
Online Access:https://www.mdpi.com/1422-0067/22/13/7080

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https://www.mdpi.com/1422-0067/22/13/7080

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