Protein Arginine Methyltransferase 6 Involved in Germ Cell Viability during Spermatogenesis and Down-Regulated by the Androgen Receptor

Protein Arginine Methyltransferase 6 Involved in Germ Cell Viability during Spermatogenesis and Down-Regulated by the Androgen Receptor

Androgens and the androgen receptor (AR) are of great importance to spermatogenesis and male fertility. AR knockout (ARKO) mice display a complete insensitivity to androgens and male infertility; however, the exact molecular mechanism for this effect remains unclear. In this study, we found that the...

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Bibliographic Details
Main Authors: Manling Luo, Yuchi Li, Huan Guo, Shouren Lin, Jianbo Chen, Qian Ma, Yanli Gu, Zhimao Jiang, Yaoting Gui
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
PRMT6
androgen receptor
testes
migration
apoptosis
Online Access:http://www.mdpi.com/1422-0067/16/12/26186

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http://www.mdpi.com/1422-0067/16/12/26186

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