Induction of Apoptosis in Human Breast Adenocarcinoma Cells MCF-7 by Monapurpyridine A, a New Azaphilone Derivative from Monascus purpureus NTU 568

Induction of Apoptosis in Human Breast Adenocarcinoma Cells MCF-7 by Monapurpyridine A, a New Azaphilone Derivative from Monascus purpureus NTU 568

A new azaphilonidal derivative, monapurpyridine A (MPA), has recently been isolated from the fermented products of Monascus purpureus NTU 568. The structure of MPA was elucidated by nuclear magnetic resonance (1H-NMR, 13C-NMR, COSY, HMQC, and HMBC) and other spectroscopic analyses. Biological evalua...

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Bibliographic Details
Main Authors: Tzu-Ming Pan, Li-Chuan Hsu, Ya-Wen Hsu, Yu-Han Liang, Chia-Ching Liaw, Yao-Haur Kuo
Format: Article
Language:English
Published: MDPI AG 2012-01-01
Series:Molecules
Subjects:
Monascus purpureus NTU 568
azaphilone
monapurpyridine A
cytotoxicity
apoptosis
Online Access:http://www.mdpi.com/1420-3049/17/1/664/

Internet

http://www.mdpi.com/1420-3049/17/1/664/

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