Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome

Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome

Long-chain acyl CoA synthetase 1 (ACSL1) plays an important role in fatty acid metabolism and triacylglycerol (TAG) synthesis. Disturbance of these pathways may result in dyslipidemia and insulin resistance, hallmarks of the metabolic syndrome (MetS). Dietary fat is a key environmental factor that m...

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Bibliographic Details
Main Authors: Catherine M. Phillips, Louisa Goumidi, Sandrine Bertrais, Martyn R. Field, L. Adrienne Cupples, Jose M. Ordovas, Catherine Defoort, Julie A. Lovegrove, Christian A. Drevon, Michael J. Gibney, Ellen E. Blaak, Beata Kiec-Wilk, Britta Karlstrom, Jose Lopez-Miranda, Ross McManus, Serge Hercberg, Denis Lairon, Richard Planells, Helen M. Roche
Format: Article
Language:English
Published: Elsevier 2010-07-01
Series:Journal of Lipid Research
Subjects:
genetic polymorphisms
insulin resistance
fatty acid metabolism
PUFA
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520371017

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http://www.sciencedirect.com/science/article/pii/S0022227520371017

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