An NF-kappaB and slug regulatory loop active in early vertebrate mesoderm.

BACKGROUND:In both Drosophila and the mouse, the zinc finger transcription factor Snail is required for mesoderm formation; its vertebrate paralog Slug (Snai2) appears to be required for neural crest formation in the chick and the clawed frog Xenopus laevis. Both Slug and Snail act to induce epithel...

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Bibliographic Details
Main Authors: Chi Zhang, Timothy F Carl, Evan D Trudeau, Thomas Simmet, Michael W Klymkowsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762408?pdf=render