Elastic Net Models Based on DNA Copy Number Variations Predicts Clinical Features, Expression Signatures, and Mutations in Lung Adenocarcinoma

Elastic Net Models Based on DNA Copy Number Variations Predicts Clinical Features, Expression Signatures, and Mutations in Lung Adenocarcinoma

In the precision medicine of lung adenocarcinoma, the identification and prediction of tumor phenotypes for specific biomolecular events are still not studied in depth. Various earlier researches sheds light on the close correlation between genetic expression signatures and DNA copy number variation...

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Bibliographic Details
Main Authors: Yi Xiang, Xiaohuan Zou, Huaqiu Shi, Xueming Xu, Caixia Wu, Wenjuan Zhong, Jinfeng Wang, Wenting Zhou, Xiaoli Zeng, Miao He, Ying Wang, Li Huang, Xiangcai Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
Elastic Net
DNA copy number
lung adenocarcinoma
gene expression signature
predictive model
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.668040/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.668040/full

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