Role of beta-arrestin 2 downstream of dopamine receptors in the basal ganglia

Role of beta-arrestin 2 downstream of dopamine receptors in the basal ganglia

Multifunctional scaffolding protein beta-arrestins (βArr) and the G protein receptor kinases (GRK) are involved in the desensitization of several G protein coupled-receptors (GPCR). However, arrestins can also contribute to GPCR signaling independently from G proteins. In this review, we focus on th...

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Bibliographic Details
Main Authors: Thomas eDel'Guidice, Morgane eLemasson, Jean-Martin eBeaulieu
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-09-01
Series:Frontiers in Neuroanatomy
Subjects:
Arrestin
Dopamine
Striatum
G protein coupled receptors
MAP kinase
Akt/protein kinase B
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2011.00058/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnana.2011.00058/full

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