Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis

Multicomponent reactions enable the rapid construction of diverse molecular scaffolds with modularity and step economy. In this work, the authors report the use of boronic acids as carbon nucleophiles in a Passerini-type three-component coupling reaction towards an expanded inventory of α-hydroxyket...

Full description

Bibliographic Details
Main Authors: Kai Yang, Feng Zhang, Tongchang Fang, Chaokun Li, Wangyang Li, Qiuling Song
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20727-7