Intermittent Hypoxia Up-Regulates Gene Expressions of <i>Peptide YY (PYY), Glucagon-like Peptide-1 (GLP-1), and Neurotensin (NTS)</i> in Enteroendocrine Cells

Intermittent Hypoxia Up-Regulates Gene Expressions of <i>Peptide YY (PYY), Glucagon-like Peptide-1 (GLP-1), and Neurotensin (NTS)</i> in Enteroendocrine Cells

The patients with sleep apnea syndrome are exposed to intermittent hypoxia (IH) during sleep. We previously demonstrated the IH-induced up-regulation of the mRNA levels of anorexigenic peptides proopiomelanocortin (POMC), and cocaine- and amphetamine-regulated transcript (CART) in human neuronal cel...

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Bibliographic Details
Main Authors: Ryogo Shobatake, Asako Itaya-Hironaka, Akiyo Yamauchi, Mai Makino, Sumiyo Sakuramoto-Tsuchida, Tomoko Uchiyama, Hiroyo Ota, Nobuyuki Takahashi, Satoshi Ueno, Kazuma Sugie, Shin Takasawa
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
sleep apnea syndrome
intermittent hypoxia
enteroendocrine cells
peptide YY
glucagon-like peptide-1
neurotensin
appetite
Online Access:https://www.mdpi.com/1422-0067/20/8/1849

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https://www.mdpi.com/1422-0067/20/8/1849

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