Selective p38α mitogen-activated protein kinase inhibitor attenuates lung inflammation and fibrosis in IL-13 transgenic mouse model of asthma

Jing Ying Ma1, Satyanarayana Medicherla1, Irene Kerr, Ruban Mangadu, Andrew A Protter, Linda S Higgins1Scios Inc, Fremont, CA, USA 1Jing Ying Ma and Satyanarayana Medicherla contributed equally to this workAbstract: p38 Mitogen-activated protein kinase (MAPK) plays a critical role in the activation...

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Bibliographic Details
Main Authors: Jing Ying Ma, Satyanarayana Medicherla, Irene Kerr, Ruban Mangadu, Andrew A Protter, Linda S Higgins
Format: Article
Language:English
Published: Dove Medical Press 2008-11-01
Series:Journal of Asthma and Allergy
Online Access:http://www.dovepress.com/selective-p38alpha-mitogen-activated-protein-kinase-inhibitor-attenuat-a2575