Membrane Transition Temperature Determines Cisplatin Response.

Cisplatin is a classical chemotherapeutic agent used in treating several forms of cancer including head and neck. However, cells develop resistance to the drug in some patients through a range of mechanisms, some of which are poorly understood. Using isolated plasma membrane vesicles as a model syst...

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Bibliographic Details
Main Authors: Krishnan Raghunathan, Aarif Ahsan, Dipankar Ray, Mukesh K Nyati, Sarah L Veatch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4618528?pdf=render