Reprograming of Tumor-Associated Macrophages in Breast Tumor-Bearing Mice under Chemotherapy by Targeting Heme Oxygenase-1

Reprograming of Tumor-Associated Macrophages in Breast Tumor-Bearing Mice under Chemotherapy by Targeting Heme Oxygenase-1

Tumor-associated macrophages (TAMs) represent one of the most abundant components of the tumor microenvironment and play important roles in tumor development and progression. TAMs display plasticity and functional heterogeneity as reflected by distinct phenotypic subsets. TAMs with an M1 phenotype h...

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Bibliographic Details
Main Authors: Seung Hyeon Kim, Su-Jung Kim, Jeongmin Park, Yeonsoo Joe, So Eui Lee, Soma Saeidi, Xiancai Zhong, Seong Hoon Kim, Sin-Aye Park, Hye-Kyung Na, Hun Taeg Chung, Young-Joon Surh
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Antioxidants
Subjects:
breast cancer
chemotherapy
tumor-associated macrophages
phagocytosis
tumor cell debris
heme oxygenase-1
Online Access:https://www.mdpi.com/2076-3921/10/3/470

Internet

https://www.mdpi.com/2076-3921/10/3/470

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